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pentobarbital will lessen the level or result of prednisone by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.pentobarbital will lessen the level or outcome of naloxegol by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Usage of naloxegol with sturdy CYP3A4 inducers just isn't suggestedpentobarbi